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Hiroshi Maeda Selected Research

Hemin (Panhematin)

6/2014Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity.
3/2012Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors.
12/2011Therapeutic potential of pegylated hemin for reactive oxygen species-related diseases via induction of heme oxygenase-1: results from a rat hepatic ischemia/reperfusion injury model.

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Hiroshi Maeda Research Topics

Disease

80Neoplasms (Cancer)
12/2022 - 03/2002
10Colonic Neoplasms (Colon Cancer)
11/2020 - 03/2002
8Neoplasm Metastasis (Metastasis)
01/2022 - 03/2002
8Periodontitis
01/2020 - 06/2003
7Inflammation (Inflammations)
08/2022 - 04/2008
6Hepatocellular Carcinoma (Hepatoma)
12/2022 - 02/2004
6Breast Neoplasms (Breast Cancer)
07/2020 - 01/2005
5Infections
10/2020 - 01/2003
5Bacterial Infections (Bacterial Infection)
12/2017 - 06/2002
4Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
03/2022 - 12/2013
4Cardiotoxicity
07/2021 - 01/2009
4Prostatic Neoplasms (Prostate Cancer)
02/2016 - 03/2004
4Carcinogenesis
12/2013 - 04/2008
3Body Weight (Weight, Body)
01/2024 - 01/2020
3BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2017 - 02/2008
3Hypertension (High Blood Pressure)
04/2016 - 11/2009
3Colitis
02/2016 - 12/2013
3Periodontal Diseases (Periodontal Disease)
09/2015 - 10/2003
3Reperfusion Injury
12/2011 - 04/2010
3Necrosis
08/2010 - 06/2003
2Chronic Granulomatous Disease
08/2022 - 06/2012
2Liver Cirrhosis (Hepatic Cirrhosis)
01/2022 - 10/2020
2Macular Degeneration (Age-Related Maculopathy)
05/2021 - 01/2011
2Thrombosis (Thrombus)
12/2020 - 10/2006
2Mycoses (Diseases, Fungus)
11/2020 - 12/2019
2Virus Diseases (Viral Diseases)
10/2020 - 01/2003

Drug/Important Bio-Agent (IBA)

15Therapeutic UsesIBA
05/2021 - 11/2004
13pirarubicinIBA
07/2021 - 01/2005
13PolymersIBA
07/2021 - 08/2007
13Antineoplastic Agents (Antineoplastics)IBA
01/2021 - 01/2003
12Styrene (Styrol)IBA
03/2022 - 03/2002
12maleic acid (maleate)IBA
03/2022 - 03/2002
10MicellesIBA
02/2016 - 06/2004
9zinc protoporphyrinIBA
05/2021 - 07/2003
9Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2016 - 03/2002
8CytokinesIBA
01/2022 - 01/2003
8Heme Oxygenase-1IBA
01/2016 - 03/2004
7Reactive Oxygen Species (Oxygen Radicals)IBA
08/2022 - 03/2004
7EnzymesIBA
08/2022 - 06/2002
7Doxorubicin (Adriamycin)FDA LinkGeneric
07/2021 - 06/2004
7Proteins (Proteins, Gene)FDA Link
01/2019 - 06/2004
7Messenger RNA (mRNA)IBA
03/2014 - 05/2002
6D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA
08/2022 - 06/2002
6Nitroglycerin (Dynamite)FDA LinkGeneric
04/2016 - 12/2009
5Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
08/2022 - 06/2002
5Carbon MonoxideIBA
03/2022 - 03/2004
5DuxonIBA
05/2021 - 02/2013
5LipidsIBA
01/2021 - 01/2003
5HydrazonesIBA
01/2021 - 01/2014
5CarcinogensIBA
07/2020 - 04/2008
5Dextran SulfateIBA
07/2020 - 12/2013
51-phenyl-3,3-dimethyltriazene (PDT)IBA
06/2019 - 11/2015
5N-(2-hydroxypropyl)methacrylamideIBA
06/2019 - 01/2014
5hydroxypropyl methacrylateIBA
01/2019 - 02/2013
5human S-nitrosoalbuminIBA
09/2017 - 02/2012
5ProstaglandinsIBA
04/2016 - 01/2003
5Evans Blue (Blue, Evans)FDA Link
11/2015 - 01/2003
4AlbuminsIBA
01/2021 - 01/2003
4anthraceneIBA
07/2020 - 12/2009
4Immunoglobulin G (IgG)IBA
01/2020 - 10/2008
4XenonIBA
09/2018 - 08/2007
4BradykininIBA
04/2016 - 03/2002
4Angiotensin IIIBA
04/2016 - 11/2009
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2016 - 06/2003
4copoly(styrene-maleic acid)-zinc protoporphyrinIBA
01/2016 - 04/2007
4Nitric Oxide Synthase (NO Synthase)IBA
10/2014 - 06/2002
4Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2014 - 02/2008
3Cisplatin (Platino)FDA LinkGeneric
12/2022 - 02/2016
3Anti-Bacterial Agents (Antibiotics)IBA
08/2022 - 10/2003
3AcidsIBA
01/2021 - 01/2014
3AzoxymethaneIBA
07/2020 - 12/2013
3Monoclonal AntibodiesIBA
01/2020 - 01/2005
3Singlet OxygenIBA
06/2019 - 08/2007
3Phosphotransferases (Kinase)IBA
03/2018 - 08/2009
3SolutionsIBA
01/2018 - 03/2008
3Xanthine OxidaseIBA
02/2016 - 04/2010
3Peptide Hydrolases (Proteases)FDA Link
01/2015 - 05/2010
3Hemin (Panhematin)FDA Link
06/2014 - 12/2011
34-vinyl-2,6-dimethoxyphenolIBA
12/2013 - 04/2008
3Peroxynitrous Acid (Peroxynitrite)IBA
07/2013 - 03/2003
3DNA (Deoxyribonucleic Acid)IBA
07/2013 - 04/2008
3Free RadicalsIBA
07/2013 - 01/2010
3Ethiodized Oil (Ethiodol)FDA Link
12/2012 - 03/2002
3poly(maleic acid-styrene)neocarzinostatin (zinostatin stimalamer)IBA
12/2012 - 03/2002
3Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
06/2012 - 06/2002
3pegylated zinc protoporphyrinIBA
08/2007 - 07/2003
2Bevacizumab (Avastin)FDA Link
12/2022 - 02/2015
2Tyrosine Kinase InhibitorsIBA
01/2022 - 01/2017
2AnthracyclinesIBA
07/2021 - 12/2009
2Glucosamine (Dona)IBA
05/2021 - 01/2021
2boric acid (boron oxide hydroxide)IBA
05/2021 - 01/2021
2Amphotericin B (Amphotericin)FDA LinkGeneric
11/2020 - 12/2019
2AntioxidantsIBA
11/2020 - 11/2005

Therapy/Procedure

30Therapeutics
01/2022 - 06/2002
12Drug Therapy (Chemotherapy)
07/2021 - 08/2007
8Photochemotherapy (Photodynamic Therapy)
05/2021 - 08/2007
6Oral Administration
01/2024 - 08/2009
3Immunotherapy
12/2022 - 01/2005
2Radiotherapy
01/2022 - 02/2016
2Precision Medicine
03/2021 - 09/2018